Key result
Compliance with nitrendipine measured by an electronic pill box was 94.4% for morning dosing and 90.6% for evening dosing, compared to 96.5% on placebo.
Why the study?
Does a microprocessor-equipped tablet box effectively monitor compliance with antihypertensive treatment in moderately hypertensive patients?
RCT (n=34)
Open-label
crossover
Does a microprocessor-equipped tablet box effectively monitor compliance with antihypertensive treatment in moderately hypertensive patients?
Absolute Event Rate: 94.4% vs 96.5%
Electronic monitoring using a microprocessor-equipped tablet box reveals high initial compliance with antihypertensive therapy that decreases over time.
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Electronic monitoring confirms high compliance (~94%) with once-daily nitrendipine; leaves open generalizability beyond small open trials.
Mallion et al. (1992) conducted an RCT in moderate hypertension (n=34). Nitrendipine vs. Placebo was evaluated on Compliance (%). Compliance with nitrendipine measured by an electronic pill box was 94.4% for morning dosing and 90.6% for evening dosing, compared to 96.5% on placebo.
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