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April 1, 1999American Journal of Hypertension

Use of electronic pill boxes to assess risk of poor treatment compliance Results of a large-scale trial

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Why the study?

What are the predictive factors of poor treatment compliance in patients with mild to moderate essential hypertension?

Population

2,173 patients with mild to moderate essential hypertension, mean age 60 +/- 12 years.

Design

Cohort, open

Follow-up

30 to 60 days

Authors

LVL Vaur

Discussion

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Overview

May warrant targeted adherence support in at-risk hypertension subgroups; leaves open efficacy of interventions in prospective trials.

Structured PICO

What are the predictive factors of poor treatment compliance in patients with mild to moderate essential hypertension?

P
Population
2,173 patients with mild to moderate essential hypertension, mean age 60 +/- 12 years.
I
Intervention
Trandolapril 2 mg once daily for 30 to 60 days in addition to usual treatment, packed in electronic pill boxes to register date and time of each opening.
O
Outcome
Predictive factors of poor compliance (correct dosing periods < 80%)

Younger age, smoking, and urban living are significant predictors of poor antihypertensive medication compliance, highlighting populations that may need targeted adherence strategies or longer-acting drugs.

Cite This Study

L Vaur (1999) studied this question.

synapsesocial.com/papers/6a7a6fa4fbd9051d3b0e475chttps://doi.org/10.1016/s0895-7061(98)00274-x
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