Key result
A 3-year weight loss intervention significantly reduced the risk of developing hypertension compared to usual care (RR 0.81; 95% CI 0.70-0.95 at 36 months).
Why the study?
Does a lifestyle-based weight loss intervention reduce blood pressure and the risk of hypertension in overweight adults with high-normal diastolic blood pressure?
Population
1,191 men and women 30 to 54 years of age who had nonmedicated diastolic blood pressure of 83 to 89 mm Hg…
Comparison
A 3-year weight loss program of group meetings… vs Usual care control.
Design
RCT, Randomly assigned, Staff who collected weight and blood pressure data…
Follow-up
36 months
Authors
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Long-term weight loss may aid BP control in at-risk adults; leaves open durability and generalizability beyond trial participants.
RCT (n=1,191)
Assessor-blind
Randomly assigned
Yes
Does a lifestyle-based weight loss intervention reduce blood pressure and the risk of hypertension in overweight adults with high-normal diastolic blood pressure?
Relative Risk: 0.81 (95% CI 0.7–0.95)
A long-term lifestyle intervention for weight loss significantly reduces blood pressure and the incidence of hypertension in overweight adults with high-normal diastolic blood pressure.
Stevens et al. (2001) conducted an RCT in Prehypertension / Overweight (n=1,191). Weight loss intervention (dietary change, physical activity, and social support) vs. Usual care control was evaluated on Incident hypertension at 36 months (RR 0.81, 95% CI 0.70-0.95). A 3-year weight loss intervention significantly reduced the risk of developing hypertension compared to usual care (RR 0.81; 95% CI 0.70-0.95 at 36 months).
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