Key result
Complement-fixing antibody to Lansing virus was detected in a subset of paralytic poliomyelitis cases, rising quickly and remaining elevated for 6 weeks to 3 months, indicating recent infection.
Why the study?
Does the presence of complement-fixing antibodies indicate recent poliomyelitis infection in humans?
Population
131 paralytic poliomyelitis cases in humans
Design
Cohort
Follow-up
up to 3 months
Authors
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May limit CF antibody for timing recent Lansing infection; leaves open its diagnostic value in immunity studies.
Observational (n=131)
Does the presence of complement-fixing antibodies indicate recent poliomyelitis infection in humans?
A positive complement-fixation test for Lansing virus may indicate recent poliomyelitis infection, as the antibody response appears transitory.
Martin Pollard (1952) conducted an observational in Paralytic poliomyelitis (n=131). Poliomyelitis infection was evaluated on Presence of complement-fixing (CF) antibody to Lansing virus. Complement-fixing antibody to Lansing virus was detected in a subset of paralytic poliomyelitis cases, rising quickly and remaining elevated for 6 weeks to 3 months, indicating recent infection.
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