Key result
DHP and PAA receptors in cardiac muscle are contained in a 185-190-kDa peptide that is significantly larger than, and structurally and immunologically different from, its skeletal muscle counterpart.
Population
Chick heart and skeletal muscle (rabbit and chick) L-type Ca2+ channels
Comparison
Purification and characterization of… vs Skeletal muscle DHP/PAA receptors (165-kDa)
Design
Preclinical
Authors
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May guide Ca channel pharmacology research; leaves open functional validation in mammalian systems.
Cardiac L-type calcium channel DHP/PAA receptors are structurally and immunologically distinct from those in skeletal muscle, being contained in a larger 185-190-kDa peptide.
Chang et al. (1988) studied this question. DHP and PAA receptors in cardiac muscle are contained in a 185-190-kDa peptide that is significantly larger than, and structurally and immunologically different from, its skeletal muscle counterpart.
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