Population
Cardiac and skeletal muscle membranes (purified skeletal muscle calcium channels and cardiac calcium channels)
Design
Preclinical
Authors
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Animal data distinguish cardiac from skeletal muscle calcium channel alpha subunits; leaves open translation to human channel function or therapy.
Basic science study demonstrating that cardiac and skeletal muscle dihydropyridine-sensitive calcium channels share homologous but distinct alpha subunits.
Takahashi et al. (1987) studied this question.
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