Key result
Following FMDV infection in pigs, no infectious virus was recovered, although FMDV RNA was transiently detected in 88% of popliteal lymph nodes at 35 days before clearing by 100 days post-infection.
Population
Convalescent pigs recovered from clinical or subclinical foot-and-mouth disease infected with any of five…
Design
Preclinical
Follow-up
Up to 100 days post-infection
Authors
Loading...
Pigs unlikely long-term infectious FMDV carriers; hypothesis-generating for lymphoid RNA persistence in livestock.
Domestic pigs are unlikely to be competent long-term carriers of infectious FMDV, although transient persistence of viral RNA and protein in lymphoid tissues is common.
Stenfeldt et al. (2014) studied Foot-and-mouth disease virus (FMDV) infection. FMDV infection was evaluated on Detection of infectious FMDV and FMDV RNA in tissues. Following FMDV infection in pigs, no infectious virus was recovered, although FMDV RNA was transiently detected in 88% of popliteal lymph nodes at 35 days before clearing by 100 days post-infection.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: