Population
Frog muscle (voltage-clamped endplates)
Comparison
Prolonged iontophoretic application of… vs Normal Ringer (1.8 mM Ca2+) without EGTA
Design
Preclinical
Authors
Loading...
Supports intracellular Ca²⁺ in ACh receptor desensitization at frog endplates; leaves open relevance to mammalian neuromuscular physiology.
Intracellular calcium plays a role in the desensitization of acetylcholine receptors in frog muscle endplates.
Ricardo Miledi (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: