Why the study?
Does enalapril improve systemic arterial structure and elastic properties in rats with myocardial infarction?
Population
40 male Wistar rats, 1 week after induction of myocardial infarction
Comparison
Enalapril 2 mg/kg for 17 weeks vs No treatment (n=20)
Design
Preclinical
Follow-up
17 weeks
Authors
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Enalapril improves arterial compliance in rat post-MI models; leaves open translation to human therapy.
Does enalapril improve systemic arterial structure and elastic properties in rats with myocardial infarction?
Long-term enalapril treatment improves arterial elastic properties and induces structural modifications of the arterial wall in rats with myocardial infarction.
Driss et al. (1999) studied this question.
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