Why the study?
Severe systemic tricuspid valve regurgitation causes morbidity and mortality after Senning or Mustard repair for D-transposition of the great arteries, making replacement useful in patients without severe ventricular dysfunction.
Transcatheter valve replacement via a trans-apical approach using an Edwards Sapien XT valve is a feasible alternative for high surgical risk patients with D-transposition of the great arteries and severe systemic tricuspid valve regurgitation.
Case experience supports feasibility of transcatheter systemic TV replacement in high-risk CHD; leaves open need for prospective validation.
Transcatheter valve replacement offers a safe and effective alternative to traditional surgical techniques in patients with congenital heart disease, especially those at high surgical risk. The most common causes of morbidity and mortality in patients with D-transposition of the great arteries status post Senning or Mustard repair is severe tricuspid valve (TV) regurgitation. Replacement of the systemic TV may be useful in those without severe systemic ventricular dysfunction. We present a case of a patient with D-loop transposition of the great arteries status post Mustard repair and TV ring placement with subsequent severe systemic TV regurgitation, at high surgical risk, who underwent a transcatheter valve replacement via a trans-apical approach using an Edwards Sapien XT valve.
No takes yet. Share an insight, caveat, or question.
Ghobrial et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: