Why the study?
Does propranolol compared to metoprolol alter haemodynamic and respiratory indices or perceived exertion during exercise in hypertensive patients?
Population
8 hypertensive patients
Comparison
Propranolol for 4 weeks vs Metoprolol for 4 weeks in a cross-over design
Design
RCT, double-blind
Follow-up
4 weeks per treatment period
Authors
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Metoprolol may be favored over propranolol for exercising hypertensive patients; extends RCT evidence on beta-blocker selectivity during activity.
Does propranolol compared to metoprolol alter haemodynamic and respiratory indices or perceived exertion during exercise in hypertensive patients?
Propranolol and metoprolol show similar antihypertensive and haemodynamic effects during exercise, though propranolol reduces peak expiratory flow rate, offering no practical advantage of one over the other for hypertension.
Herwaarden et al. (1979) studied this question.
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