Why the study?
Does thyroid status influence the postnatal maturation of dihydropyridine receptors in rat ventricles?
Population
Newborn rats
Comparison
L-triiodothyronine or 6-n-propyl-2-thiouracil… vs Control rats
Design
Preclinical
Follow-up
Up to postnatal day 14
Authors
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Thyroid status modulates DHPR maturation in developing rat ventricle; leaves open relevance to human neonatal thyroid-cardiac interactions.
Does thyroid status influence the postnatal maturation of dihydropyridine receptors in rat ventricles?
Hypothyroidism impairs the early postnatal maturation and subcellular localization of dihydropyridine receptors in rat ventricles.
Wibo et al. (1998) studied this question.
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