Population
Rat ventricular myocytes from newborn to 20-day-old rats
Comparison
Alteration of thyroid hormone levels vs Age-matched control animals
Design
Preclinical
Authors
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Supports thyroid hormone regulation of neonatal rat It; leaves open human developmental or clinical relevance.
Thyroid hormone regulates the postnatal development of the transient outward K+ current and its underlying Kv4.2 and Kv4.3 channel isoforms in rat ventricular myocytes.
Shimoni et al. (1997) studied this question.
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