Why the study?
Does wideband high-frequency echocardiography accurately evaluate myocardial infarct size, location, and morphologic changes in vivo in a rat model?
Population
48 rats (41 with left anterior descending coronary artery ligation, 7 sham control)
Comparison
Wideband high-frequency echocardiography vs Histologic analysis
Design
Preclinical
Authors
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Supports noninvasive infarct assessment in rat models; leaves open clinical translation.
Does wideband high-frequency echocardiography accurately evaluate myocardial infarct size, location, and morphologic changes in vivo in a rat model?
Wideband high-frequency echocardiography is a feasible in vivo method for evaluating myocardial infarct size and remodeling in rat models.
Xu et al. (2009) studied this question.
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