Population
rabbit reticulocyte lysates (RRL) programmed with poliovirus type 1 (Mahoney) RNA
Design
Preclinical
Authors
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La may specifically enhance accurate poliovirus translation in vitro; leaves open extension to cellular models or antiviral targeting.
La protein specifically stimulates correct internal translation initiation of poliovirus RNA and inhibits aberrant translation products in vitro.
Svitkin et al. (1994) studied this question.
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