Population
Picornavirus RNAs (poliovirus and encephalomyocarditis virus)
Design
Review
Authors
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May guide antiviral strategies targeting IRES; leaves open clinical validation in human viral infections.
Picornaviruses utilize a unique cap-independent internal translation initiation mechanism via the internal ribosome entry site (IRES).
Ellie Ehrenfeld (1996) studied this question.
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