Why the study?
Does intracoronary tetraethylammonium chloride combined with electrical shock achieve defibrillation in hypothermic canine hearts with magnesium-induced ventricular fibrillation?
Population
Isolated canine hearts and intact animals undergoing hypothermia with ventricular fibrillation induced by…
Comparison
Intracoronary injection of tetraethylammonium… vs Other means of defibrillation
Design
Preclinical
Authors
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Enables defibrillation in experimental hypothermic VF; leaves open translation to human resuscitation.
Does intracoronary tetraethylammonium chloride combined with electrical shock achieve defibrillation in hypothermic canine hearts with magnesium-induced ventricular fibrillation?
Tetraethylammonium chloride combined with electrical shock enables defibrillation in hypothermic canine hearts where other methods fail.
Caldini et al. (1958) studied this question.
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