Population
Conscious rats developing one-kidney, one clip (1K1C) renal hypertension
Comparison
Development of renal hypertension and… vs Sham-operated rats and normotensive control rats
Design
Preclinical
Follow-up
30 days
Authors
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No immediate clinical implications; leaves open mechanistic roles of transient tachycardia in sustaining experimental renal hypertension.
In a rat model of renal hypertension, an initial transient tachycardia accompanies the early rise in blood pressure, which is later sustained despite normalization of heart rate.
Machado et al. (1983) studied this question.
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