Population
Conscious one-kidney, one clip (1-K,1C) hypertensive rats and conscious normotensive rats
Comparison
Renal hypertension induction, 3-hour infusion of… vs Baseline or control conditions
Design
Preclinical
Follow-up
14 days
Authors
Loading...
Angiotensin II may drive intrinsic heart rate elevation in experimental renovascular hypertension; leaves open relevance to human tachycardia and requires clinical validation.
The tachycardia observed during the onset of 1-K,1C renal hypertension in rats may be partly driven by an angiotensin II-mediated increase in intrinsic heart rate.
Machado et al. (1987) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: