A method for the determination in anæsthetized dogs of the right and left cardiac outputs has been described; it depends upon accurate and fast recording of the blood temperature changes which occur in the right ventricle and aorta when cold Ringer solution or blood is injected into the inferior vena cava. The curves defining the blood temperature changes are time‐concentration curves, from which the blood flow at the sites of the recording thermocouples can be estimated with an accuracy which is roughly the accuracy of the Fick method. Various errors to which the technique may be subject are considered; attempts have been made to compute their effects quantitatively. The method is here described as the “thermo‐dilution” method.
George Fegler (Mon,) studied this question.