Why the study?
Does ACE genotype influence blood pressure response to dietary sodium changes in older hypertensive patients?
Does ACE genotype influence blood pressure response to dietary sodium changes in older hypertensive patients?
The ACE gene ID and DD genotypes are associated with sodium sensitivity and increased blood pressure on a high sodium diet in older hypertensive patients.
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ACE II genotype may blunt BP response to high sodium in older hypertensives; leaves open whether genotyping should guide dietary advice.
Donald R. Dengel (2001) studied this question.
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