Population
Mammalian sinoatrial node cells and subsidiary pacemaker atrioventricular node cells
Design
Review
Authors
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Suggests I(st) contributes to SA node automaticity; leaves open its potential as a therapeutic target pending direct studies.
The sustained inward current (I(st)) plays a crucial role in generating intrinsic cardiac automaticity in mammalian pacemaker cells.
Mitsuiye et al. (2000) studied this question.