Why the study?
Do diltiazem, atenolol, or enalapril differ in improving blood pressure control and quality of life in older hypertensive women?
Population
242 older hypertensive women
Comparison
Diltiazem 60 to 180 mg twice a day, atenolol 50… vs Active comparators
Design
RCT, randomized, parallel group, double-blind
Follow-up
16 weeks
Authors
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Supports diltiazem preference for diastolic BP control in older hypertensive women; extends RCT head-to-head comparisons among these agents.
Do diltiazem, atenolol, or enalapril differ in improving blood pressure control and quality of life in older hypertensive women?
Diltiazem provided greater diastolic blood pressure lowering than atenolol or enalapril in older hypertensive women, with equivalent adverse events and quality of life.
William B. Applegate (1991) studied this question.
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