Why the study?
Do atenolol, enalapril, or diltiazem differ in their effects on blood pressure control and quality of life in older hypertensive women?
Population
242 older hypertensive women
Comparison
Titrated doses of atenolol, enalapril, or… vs Active comparators
Design
RCT, randomized, parallel group, double-blind
Follow-up
16 weeks
Authors
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Diltiazem yields modestly greater diastolic BP reduction in older hypertensive women; extends head-to-head RCT comparisons among these agents.
Do atenolol, enalapril, or diltiazem differ in their effects on blood pressure control and quality of life in older hypertensive women?
Atenolol, enalapril, and diltiazem are all effective and well-tolerated for lowering blood pressure in older hypertensive women, though diltiazem demonstrated slightly greater diastolic blood pressure reduction and a lower treatment failure rate.
William B. Applegate (1991) studied this question.
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