Why the study?
Does amlodipine compared to enalapril improve quality of life and blood pressure in patients with mild or moderate hypertension?
Population
461 patients of both sexes with mild or moderate hypertension
Comparison
Amlodipine 5-10 mg/day for 1 year vs Enalapril 10-40 mg/day for 1 year
Design
RCT, parallel allocation, double-blind, double-dummy
Follow-up
1 year
Authors
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Either agent suits mild-moderate hypertension; confirms comparable blood pressure control and quality-of-life preservation in this RCT.
Does amlodipine compared to enalapril improve quality of life and blood pressure in patients with mild or moderate hypertension?
Amlodipine and enalapril are equally effective at reducing blood pressure and maintaining quality of life in patients with mild to moderate hypertension.
Omvik et al. (1993) studied this question.
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