Why the study?
Do ACE and AT1R polymorphisms affect the risk of myocardial infarction differently in men and women?
Do ACE and AT1R polymorphisms affect the risk of myocardial infarction differently in men and women?
The ACE polymorphism may have heterogeneous effects on myocardial infarction risk between men and women, whereas the AT1R1196 polymorphism is not an independent risk factor in either sex.
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May suggest sex-heterogeneous ACE effects on MI risk; leaves open causal role pending larger prospective studies.
Kee et al. (2000) studied this question.
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