Why the study?
Is the ACE gene I/D polymorphism associated with myocardial infarction and coronary stenosis in patients undergoing coronary angiography?
Is the ACE gene I/D polymorphism associated with myocardial infarction and coronary stenosis in patients undergoing coronary angiography?
The ACE I/D polymorphism D allele is a significant genetic risk factor for myocardial infarction but does not appear to influence the development of coronary atherostenosis.
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May support ACE I/D as MI risk marker in stenotic men; leaves open causality and clinical utility pending prospective validation.
Ludwig et al. (1995) studied this question.
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