Population
Two independently isolated defective interfering (DI) RNA populations of Sindbis virus
Comparison
Determination of 5'-terminal nucleotide… vs Standard Sindbis viral RNA
Design
Preclinical
Authors
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Cellular tRNA capture by Sindbis DI particles may shape viral interference; leaves open relevance to other viruses or mammalian pathogenesis.
The study demonstrates that defective interfering particles of Sindbis virus incorporate a cellular tRNA sequence at their 5' ends.
Monroe et al. (1983) studied this question.
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