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July 1, 1989Cardiovascular Research

Solute transfer into the extravascular space: comparison of two non-invasive measurement techniques

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Population

60 subjects, including those with normal renal function

Design

Other

Authors

APA. M. PetersHarley-Davidson (United States)MMM J MyersSt. Catherine University

Discussion

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Implication

May support t95 validation as permeability marker; leaves open clinical adoption pending prospective trials.

Structured PICO

P
Population
60 subjects, including those with normal renal function
I
Intervention
Non-invasive measurement of microvascular permeability using 99mTc DTPA clearance via gamma camera (regional clearance PSr and whole body index t95)
O
Outcome
Correlation between whole body microvascular permeability index (t95) and regional clearance (PSr)surrogate

A novel non-invasive gamma camera technique using 99mTc DTPA clearance provides a simple method to quantify regional and whole-body microvascular permeability.

Cite This Study

Peters et al. (1989) studied this question.

synapsesocial.com/papers/6a7028a8febe604dd708f487https://doi.org/10.1093/cvr/23.7.639
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Measurement of the blood‐brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts1991 · 1,473 citations
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  4. 4Regional myocardial flow and capillary permeability-surface area products are nearly proportional1994 · 68 citations
  5. 5The penetration of inulin, sucrose, mannitol and tritiated water from the interstitial space in muscle into the vascular system1970 · 33 citations