May 19, 2014Circulation Arrhythmia and Electrophysiology

The Epidemic of Inadequate Biventricular Pacing in Patients With Persistent or Permanent Atrial Fibrillation and Its Association With Mortality

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Why the study?

Does atrial fibrillation burden and reduced biventricular pacing increase mortality in CRT-D patients?

Population

54,019 cardiac resynchronization therapy defibrillator (CRT-D) patients, mean age 70±11 years, 73% male.

Comparison

Atrial fibrillation and reduced biventricular… vs No/little atrial fibrillation and high…

Design

Cohort

Follow-up

2.3±1.2 years

Authors

KOKevin T. Ousdigian PBPeter Borek JKJodi Koehler

Discussion

Member takes

Overview

Persistent AF or BIVP <90% linked to higher mortality in CRT-D patients; hypothesis-generating for targeted interventions, prospective trials needed.

Structured PICO

Does atrial fibrillation burden and reduced biventricular pacing increase mortality in CRT-D patients?

Population

54,019 cardiac resynchronization therapy defibrillator (CRT-D) patients, mean age 70±11 years, 73% male.

Intervention

Atrial fibrillation (permanent, persistent, or paroxysmal) and reduced biventricular pacing (BIVP <98%)

Comparator

No/little atrial fibrillation and high biventricular pacing (BIVP >98%)

Outcome

All-cause mortalityhard clinical

In CRT-D patients, persistent or permanent AF is associated with inadequate biventricular pacing (<98%), which independently correlates with increased all-cause mortality.

Cite This Study

Ousdigian et al. (2014) studied this question.

synapsesocial.com/papers/6a703fc7e36a167817e2007e https://doi.org/10.1161/circep.113.001212

View Full Paper

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May 19, 2014Circulation Arrhythmia and Electrophysiology

The Epidemic of Inadequate Biventricular Pacing in Patients With Persistent or Permanent Atrial Fibrillation and Its Association With Mortality

View Full Paper

Ask AI

Bookmark

Why the study?

Does atrial fibrillation burden and reduced biventricular pacing increase mortality in CRT-D patients?

Population

54,019 cardiac resynchronization therapy defibrillator (CRT-D) patients, mean age 70±11 years, 73% male.

Comparison

Atrial fibrillation and reduced biventricular… vs No/little atrial fibrillation and high…

Design

Cohort

Follow-up

2.3±1.2 years

Authors

KOKevin T. Ousdigian PBPeter Borek JKJodi Koehler

Discussion

Member takes

Overview

Persistent AF or BIVP <90% linked to higher mortality in CRT-D patients; hypothesis-generating for targeted interventions, prospective trials needed.

Structured PICO

Does atrial fibrillation burden and reduced biventricular pacing increase mortality in CRT-D patients?

Population

54,019 cardiac resynchronization therapy defibrillator (CRT-D) patients, mean age 70±11 years, 73% male.

Intervention

Atrial fibrillation (permanent, persistent, or paroxysmal) and reduced biventricular pacing (BIVP <98%)

Comparator

No/little atrial fibrillation and high biventricular pacing (BIVP >98%)

Outcome

All-cause mortalityhard clinical

In CRT-D patients, persistent or permanent AF is associated with inadequate biventricular pacing (<98%), which independently correlates with increased all-cause mortality.

Cite This Study

Ousdigian et al. (2014) studied this question.

synapsesocial.com/papers/6a703fc7e36a167817e2007e https://doi.org/10.1161/circep.113.001212

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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