Key result
Pre-procedural atrial fibrillation was associated with a higher risk of heart failure hospitalization or death compared to sinus rhythm (73.8% vs 42.6%; HR 8.949, 95% CI 2.429-32.972, p=0.001).
Why the study?
Does pre-procedural atrial fibrillation worsen outcomes (hospitalization due to HF or death) in heart failure patients treated with cardiac resynchronization therapy?
Population
118 heart failure patients undergoing cardiac resynchronization therapy implantation, mean age 69±11 years…
Comparison
Pre-procedural atrial fibrillation (AF) vs Sinus rhythm (SR)
Design
Cohort
Follow-up
mean 43±18 months
Authors
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May warrant intensified monitoring in CRT recipients with pre-procedural AF; leaves open whether rhythm control alters outcomes.
Cohort (n=118)
Does pre-procedural atrial fibrillation worsen outcomes (hospitalization due to HF or death) in heart failure patients treated with cardiac resynchronization therapy?
Hazard Ratio: 8.949 (95% CI 2.429–32.972)
Absolute Event Rate: 73.8% vs 42.6%
p-value: p=0.001
Pre-procedural atrial fibrillation and lower biventricular pacing percentages are strong independent predictors of increased mortality and heart failure hospitalization in patients receiving cardiac resynchronization therapy.
Pereira et al. (2021) conducted a cohort in Heart failure treated with cardiac resynchronization therapy (CRT) (n=118). Pre-procedural atrial fibrillation vs. Sinus rhythm was evaluated on Composite endpoint of hospitalization due to HF or death for any cause (HR 8.949, 95% CI 2.429-32.972, p=0.001). Pre-procedural atrial fibrillation was associated with a higher risk of heart failure hospitalization or death compared to sinus rhythm (73.8% vs 42.6%; HR 8.949, 95% CI 2.429-32.972, p=0.001).
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