Effect of paracetamol (N-acetyl-p-aminophenol) on gastrointestinal bleeding

EDITORIAL SYNOPSIS This paper gives firm scientific proof to the already prevailing view that paracetamol does not cause bleeding from the stomach and is an acceptable alternative to aspirin. There is now ample evidence that the oral admini-stration of aspirin leads to an increase in faecal blood loss in the majority of normal people. Some investigators (Lange, 1957; Alvarez and Summerskill 1958; Stubbe, Pietersen, and Van Heulen, 1962)