What is the clinical evidence from this study?

Study design: Cohort. Population: Chronic heart failure (stages A/B/C/D) (n=7292). Intervention: High physical activity level vs. Low physical activity level. Primary outcome: All-cause death, acute myocardial infarction, stroke, heart failure hospitalization, and other cardiovascular events (p=<0.05).

January 1, 2013Circulation JournalOpen Access

Impact of Physical Activity on Cardiovascular Events in Patients With Chronic Heart Failure

Q: What are the key findings of this study?

Higher baseline physical activity and its maintenance over time were significantly associated with lower risks of all-cause death, heart failure hospitalization, and other major cardiovascular events in patients with chronic heart failure.

View Full Paper

Ask AI

Bookmark

Key result

Higher baseline physical activity and its maintenance over time were significantly associated with lower risks of all-cause death, heart failure hospitalization, and other major cardiovascular events in patients with chronic heart failure.

Why the study?

Does high physical activity reduce cardiovascular events and mortality in patients with chronic heart failure?

Population

9,178 patients with stage A/B/C/D chronic heart failure in Japan. Baseline physical activity data available…

Comparison

High physical activity vs Low physical activity (below the median value)

Design

Cohort

Follow-up

3-year follow-up period (mean 1.4±0.01 years)

Authors

YMYutaka Miura YFYoshihiro Fukumoto TMToshiro Miura

Discussion

Member takes

Overview

Supports activity monitoring in chronic HF; leaves open whether interventions to increase activity improve outcomes.

Study Design

Type

Cohort (n=7,292)

Multicenter

Yes

Structured PICO

Does high physical activity reduce cardiovascular events and mortality in patients with chronic heart failure?

Population

7,292 patients with stage A/B/C/D chronic heart failure in Japan, followed for a mean of 1.4 years to assess the impact of physical activity on cardiovascular events.

Exposure

High physical activity (above the median value of 8.9 Ex in men/7.6 Ex in women for stage A/B, and 8.0 Ex in men/6.6 Ex in women for stage C/D)

Comparator

Low physical activity (below the median value)

Outcome

All-cause death, acute myocardial infarction (AMI), stroke, heart failure (HF) hospitalization, and other cardiovascular events (except AMI, stroke, and HF hospitalization)hard clinical

Main Result

p-value: p=<0.05

Higher baseline physical activity and the maintenance of physical activity over time are associated with reduced mortality and cardiovascular events in patients with chronic heart failure.

Limitations

Physical activity level was evaluated only by subjective questionnaire, not by objective methods.
Patients were simply divided by the median value of physical activity to evaluate yearly change.
Some data were lacking for a relatively large number of CHF patients.
Unable to clarify whether a decrease in physical activity was a cause or a result of cardiovascular diseases.
Potential confounding by indication, as use of protective HF drugs was associated with worsening HF, likely due to administration in more severe cases.
Physical activity level was evaluated only by subjective questionnaire, not by objective methods
Patients were simply divided by the median value of physical activity to evaluate yearly changes
Some data were lacking despite the large cohort size

Cite This Study

Miura et al. (2013) conducted a cohort in Chronic heart failure (stages A/B/C/D) (n=7,292). High physical activity level vs. Low physical activity level was evaluated on All-cause death, acute myocardial infarction, stroke, heart failure hospitalization, and other cardiovascular events (p=<0.05). Higher baseline physical activity and its maintenance over time were significantly associated with lower risks of all-cause death, heart failure hospitalization, and other major cardiovascular events in patients with chronic heart failure.

synapsesocial.com/papers/6a7064cb26a7f98052dce4b2 https://doi.org/10.1253/circj.cj-13-0746

View Full Paper

Ask AI

Bookmark

January 1, 2013Circulation JournalOpen Access

Impact of Physical Activity on Cardiovascular Events in Patients With Chronic Heart Failure

View Full Paper

Ask AI

Bookmark

Key result

Why the study?

Does high physical activity reduce cardiovascular events and mortality in patients with chronic heart failure?

Population

9,178 patients with stage A/B/C/D chronic heart failure in Japan. Baseline physical activity data available…

Comparison

High physical activity vs Low physical activity (below the median value)

Design

Cohort

Follow-up

3-year follow-up period (mean 1.4±0.01 years)

Authors

YMYutaka Miura YFYoshihiro Fukumoto TMToshiro Miura

Discussion

Member takes

Overview

Supports activity monitoring in chronic HF; leaves open whether interventions to increase activity improve outcomes.

Study Design

Type

Cohort (n=7,292)

Multicenter

Yes

Structured PICO

Does high physical activity reduce cardiovascular events and mortality in patients with chronic heart failure?

Population

7,292 patients with stage A/B/C/D chronic heart failure in Japan, followed for a mean of 1.4 years to assess the impact of physical activity on cardiovascular events.

Exposure

High physical activity (above the median value of 8.9 Ex in men/7.6 Ex in women for stage A/B, and 8.0 Ex in men/6.6 Ex in women for stage C/D)

Comparator

Low physical activity (below the median value)

Outcome

All-cause death, acute myocardial infarction (AMI), stroke, heart failure (HF) hospitalization, and other cardiovascular events (except AMI, stroke, and HF hospitalization)hard clinical

Main Result

p-value: p=<0.05

Higher baseline physical activity and the maintenance of physical activity over time are associated with reduced mortality and cardiovascular events in patients with chronic heart failure.

Limitations

Physical activity level was evaluated only by subjective questionnaire, not by objective methods.
Patients were simply divided by the median value of physical activity to evaluate yearly change.
Some data were lacking for a relatively large number of CHF patients.
Unable to clarify whether a decrease in physical activity was a cause or a result of cardiovascular diseases.
Potential confounding by indication, as use of protective HF drugs was associated with worsening HF, likely due to administration in more severe cases.
Physical activity level was evaluated only by subjective questionnaire, not by objective methods
Patients were simply divided by the median value of physical activity to evaluate yearly changes
Some data were lacking despite the large cohort size

Cite This Study

synapsesocial.com/papers/6a7064cb26a7f98052dce4b2 https://doi.org/10.1253/circj.cj-13-0746

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark