Why the study?
Does standard-dose intracoronary streptokinase improve reperfusion compared to low-dose in patients with acute myocardial infarction?
Does standard-dose intracoronary streptokinase improve reperfusion compared to low-dose in patients with acute myocardial infarction?
Standard-dose intracoronary streptokinase is significantly more effective than low-dose at achieving reperfusion in acute myocardial infarction, and successful reperfusion is strongly associated with the development of a systemic lytic state.
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Standard-dose intracoronary streptokinase was associated with higher reperfusion than low-dose; leaves open optimal dosing and clinical benefit in randomized acute MI trials.
Rothbard et al. (1985) studied this question.
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