Why the study?
Is central systolic blood pressure associated with the presence of silent cerebral lacunar infarcts in an asymptomatic general population?
Population
500 Japanese individuals free from symptomatic cardiovascular diseases, mean age 66.9 +/- 8.4 years.
Comparison
Second peak radial systolic BP as an estimate of… vs Carotid flow augmentation index and brachial BP
Design
Cross-sectional
Authors
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Radial SBP2 may flag silent lacunar infarcts in asymptomatic adults; hypothesis-generating, requires prospective validation before clinical adoption.
Is central systolic blood pressure associated with the presence of silent cerebral lacunar infarcts in an asymptomatic general population?
Central systolic blood pressure, estimated by second peak radial systolic BP, is significantly associated with silent cerebral small vessel disease in an apparently healthy general population.
Ochi et al. (2010) studied this question.
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