Key result
Transpulmonary thermodilution-derived cardiac function index was significantly lower in patients with acute heart failure compared to septic patients (median 2.8 vs 6.1 1/min, p<0.001).
Why the study?
Does transpulmonary thermodilution-derived cardiac function index correlate with pulmonary artery catheter measurements to identify cardiac dysfunction in critically ill patients with AHF or sepsis?
Population
21 critically ill medical patients in an intensive care unit, including 12 with acute heart failure and 9…
Comparison
Hemodynamic assessment using single-indicator… vs Hemodynamic assessment using pulmonary artery…
Design
Cohort
Follow-up
24-hour observation period
Authors
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May distinguish cardiac dysfunction in acute heart failure from sepsis; leaves open validation against pulmonary artery catheter.
Observational (n=21)
No
Does transpulmonary thermodilution-derived cardiac function index correlate with pulmonary artery catheter measurements to identify cardiac dysfunction in critically ill patients with AHF or sepsis?
Absolute Event Rate: 2.8% vs 6.1%
p-value: p=<0.001
Transpulmonary thermodilution is a viable alternative to the pulmonary artery catheter for assessing cardiac function and identifying cardiac dysfunction in critically ill patients with acute heart failure or sepsis.
Ritter et al. (2009) conducted an observational in Acute heart failure and severe sepsis or septic shock (n=21). Acute heart failure vs. Severe sepsis or septic shock was evaluated on Cardiac function index (CFI) in 1/minute (p=<0.001). Transpulmonary thermodilution-derived cardiac function index was significantly lower in patients with acute heart failure compared to septic patients (median 2.8 vs 6.1 1/min, p<0.001).
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