Population
Conscious chronic renal hypertensive rats (RHR; 1K-1C, 2 mo)
Comparison
Reversal of hypertension by unclipping the renal… vs Control conditions and normotensive control rats
Design
Preclinical
Follow-up
2 hours
Authors
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Hypertension reversal fails to restore baroreflex bradycardia in renal hypertensive rats; leaves open the time course of autonomic recovery for clinical translation.
In chronic renal hypertensive rats, normalization of baroreceptor gain occurs early after hypertension reversal but independent of the recovery of baroreflex control over heart rate.
Farah et al. (2001) studied this question.
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