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October 1, 1994Clinical and Experimental Pharmacology and Physiology

Cardiac Baroreflexes and Hypertension

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Population

Hypertensive humans and animals (including spontaneously hypertensive rats [SHR] and Wistar-Kyoto rats [WKY])

Design

Review

Authors

GHGeoffrey A. HeadPreventive Cardiology

Discussion

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Implication

May link cardiac hypertrophy to vagal deficits more than BP in hypertension; leaves open translation to human baroreflex therapies.

Structured PICO

P
Population
Hypertensive humans and animals (including spontaneously hypertensive rats [SHR] and Wistar-Kyoto rats [WKY])

Antihypertensive therapy that effectively reduces cardiac hypertrophy may improve baroreceptor reflexes and reduce blood pressure variability, potentially lowering the risk of sudden death.

Cite This Study

Geoffrey A. Head (1994) studied this question.

synapsesocial.com/papers/6a7e025ac108c8d3ff046381https://doi.org/10.1111/j.1440-1681.1994.tb02448.x

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Baroreflexes and Cardiovascular Regulation in Hypertension1995 · 83 citations
  2. 2Cardiovascular reflexes and hypertension.1991 · 55 citations
  3. 3BARORECEPTOR RESETTING AND OTHER DETERMINANTS OF BAROREFLEX PROPERTIES IN HYPERTENSION1989 · 69 citations
  4. 4Structural cardiovascular adaptation and the consequences for baroreflexes.1984 · 11 citations
  5. 5Relationship between cardiovascular hypertrophy and cardiac baroreflex function in spontaneously hypertensive and stroke-prone rats1993 · 69 citations