November 1, 1984Hypertension
Structural cardiovascular adaptation and the consequences for baroreflexes.
Population
Experimental models (young spontaneously hypertensive rats) and human patients with borderline hypertension
Design
Review
Authors
Discussion
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Implication
Caution against practice changes in hypertension; leaves open baroreflex-targeted interventions pending prospective human confirmation.
Structured PICO
P
Population
Experimental models (young spontaneously hypertensive rats) and human patients with borderline hypertension
In hypertension, structural cardiovascular adaptations and reduced venous compliance lead to a resetting of baroreflex mechanisms to maintain homeostasis at higher blood pressures.
Cite This Study
Zanchetti et al. (1984) studied this question.