July 1, 1988American Journal of Hypertension
Cardiopulmonary Receptor Reflex in Hypertension
Why the study?
Does antihypertensive treatment improve cardiopulmonary reflex function in patients with hypertension and left ventricular hypertrophy?
Population
Normotensive humans, experimental animal models, and patients with essential hypertension
Design
Review
Authors
Discussion
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Implication
Antihypertensive-induced LVH regression may restore cardiopulmonary reflex function; leaves open confirmation of clinical benefit in prospective trials.
Structured PICO
Does antihypertensive treatment improve cardiopulmonary reflex function in patients with hypertension and left ventricular hypertrophy?
P
Population
Normotensive humans, experimental animal models, and patients with essential hypertension (mild, moderate, and with left ventricular hypertrophy)
I
Intervention
Antihypertensive treatment
O
Outcome
Cardiopulmonary reflex function (inhibitory control of sympathetic vasomotor and renin influences)surrogate
Antihypertensive treatment can reverse the impairment of the cardiopulmonary reflex associated with left ventricular hypertrophy in hypertensive patients.
Cite This Study
Mancia et al. (1988) studied this question.