Key result
Cardiopulmonary receptor control of skeletal muscle circulation and renin release is maintained in mild-to-moderate hypertension but may be impaired in severe hypertension with cardiac hypertrophy.
Population
Humans with normal and high arterial blood pressure (normotensive and essential hypertensive subjects)
Design
Review
Authors
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Preserves standard management in mild-to-moderate hypertension; leaves open targeted approaches for severe cases with hypertrophy pending prospective data.
Cardiopulmonary volume receptors play a key role in modulating skeletal muscle circulation and renin release, a mechanism that becomes impaired in severe essential hypertension with cardiac hypertrophy.
Grassı et al. (1987) conducted a review in Normal and high arterial blood pressure. Cardiopulmonary receptor deactivation and stimulation was evaluated on Forearm vascular resistance and plasma renin activity. Cardiopulmonary receptor control of skeletal muscle circulation and renin release is maintained in mild-to-moderate hypertension but may be impaired in severe hypertension with cardiac hypertrophy.
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