Why the study?
Does antihypertensive pharmacological treatment restore cardiopulmonary reflex control of circulation in subjects with cardiac hypertrophy?
Population
Subjects with cardiac hypertrophy, specifically severe hypertensive subjects and athletes.
Design
Review
Authors
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Cardiac hypertrophy impairs cardiopulmonary reflexes with partial restoration after regression; leaves open whether this improves outcomes or warrants targeted therapy.
Does antihypertensive pharmacological treatment restore cardiopulmonary reflex control of circulation in subjects with cardiac hypertrophy?
Cardiac hypertrophy itself impairs cardiopulmonary reflex control of circulation, which can be partially restored by antihypertensive therapy that induces structural regression.
Grassı et al. (1990) studied this question.
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