June 1, 1984Journal of Clinical Oncology
Intrapericardial tetracycline sclerosis in the treatment of malignant pericardial effusion: an analysis of thirty-three cases.
Why the study?
Does intrapericardial instillation of tetracycline hydrochloride control signs and symptoms of tamponade in patients with malignant pericardial effusion?
Population
33 unselected patients with cardiac tamponade secondary to malignant pericardial effusion
Design
Case_series
Follow-up
28-704 days (survival range)
Authors
Discussion
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Member takes
Implication
May support tetracycline sclerosis for malignant tamponade palliation; leaves open confirmation in prospective trials.
Structured PICO
Does intrapericardial instillation of tetracycline hydrochloride control signs and symptoms of tamponade in patients with malignant pericardial effusion?
P
Population
33 unselected patients with cardiac tamponade secondary to malignant pericardial effusion
I
Intervention
Intrapericardial instillation of tetracycline hydrochloride
O
Outcome
Complete control of the initial signs and symptoms of tamponadehard clinical
Intrapericardial tetracycline sclerosis is a safe, simple, and efficacious palliative treatment for cardiac tamponade secondary to malignant pericardial effusion.
Cite This Study
Davis et al. (1984) studied this question.