Key result
Intracavitary oxytetracycline resulted in rapidly improving symptoms in all 11 patients with malignant pericardial tamponade, with no pericardial relapse over a median 9-month follow-up.
Why the study?
Does intracavitary oxytetracycline improve symptoms and prevent relapse in patients with malignant pericardial tamponade?
Population
11 consecutive patients with malignant pericardial tamponade
Design
Case_series
Follow-up
median 9 months
Authors
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May warrant consideration in refractory malignant pericardial tamponade; leaves open efficacy and safety pending prospective trials.
Observational (n=11)
Does intracavitary oxytetracycline improve symptoms and prevent relapse in patients with malignant pericardial tamponade?
Intracavitary oxytetracycline is an effective and well-tolerated treatment for malignant pericardial tamponade, providing durable relief without pericardial relapse.
Grau et al. (2009) conducted an observational in Malignant pericardial tamponade (n=11). Intracavitary oxytetracycline was evaluated on Response to treatment (rapidly improving symptoms). Intracavitary oxytetracycline resulted in rapidly improving symptoms in all 11 patients with malignant pericardial tamponade, with no pericardial relapse over a median 9-month follow-up.
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