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No immediate change to human aortic insufficiency care; leaves open translation of canine coronary flow alterations.
In dogs with chronic aortic insufficiency accompanied by cardiac hypertrophy, the coronary blood flow, cardiac oxygen consumption, coronary arteriovenous oxygen difference, coronary oxygen utilization, systolic pressure and cardiac rate are increased significantly above the normals, while coronary venous oxygen saturation, coronary resistance and diastolic pressure are significantly decreased.
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West et al. (1959) studied this question.
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