Why the study?
Does systemic hypertension affect ischemic and nonischemic regional left ventricular function in dogs after experimental coronary occlusion?
Does systemic hypertension affect ischemic and nonischemic regional left ventricular function in dogs after experimental coronary occlusion?
In a canine model of myocardial infarction, prolonged mild systemic hypertension accentuates end-diastolic wall thinning in ischemic segments, although shorter durations do not significantly impair oxygen supply and demand.
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Prolonged mild hypertension may worsen ischemic wall thinning in canine MI models; leaves open duration effects and human relevance.
Roan et al. (1982) studied this question.
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