Why the study?
Does indapamide 1.25 mg/day reduce sitting diastolic blood pressure in elderly patients with mild to moderate essential hypertension?
Population
222 elderly patients (≥50 years) with mild to moderate essential hypertension
Comparison
Indapamide 1.25 mg/day for 8 weeks vs Placebo
Design
RCT, Randomized, parallel-group, Double-blind
Follow-up
8 weeks
Authors
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Supports low-dose indapamide for BP control in elderly hypertensives; confirms placebo-controlled efficacy in mild-to-moderate hypertension.
Does indapamide 1.25 mg/day reduce sitting diastolic blood pressure in elderly patients with mild to moderate essential hypertension?
Low-dose indapamide (1.25 mg/day) effectively reduces blood pressure in elderly patients with mild to moderate hypertension without clinically significant metabolic adverse effects.
Weidler et al. (1995) studied this question.
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