Why the study?
Does the time of day (morning vs. afternoon) affect the physiological responses associated with initial and delayed orthostatic hypotension in normotensive volunteers?
Population
17 normotensive volunteers, aged 26 ± 1 yrs (mean ± SE)
Comparison
Postural change protocol performed at 06:00 h vs Same postural change protocol performed at 16:00 h
Design
Other
Authors
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No diurnal variation in orthostatic MAP responses; leaves open other mechanisms for time-of-day effects on tolerance.
Does the time of day (morning vs. afternoon) affect the physiological responses associated with initial and delayed orthostatic hypotension in normotensive volunteers?
There is no diurnal variation in the onset of and physiological responses associated with initial and delayed orthostatic hypotension in young normotensive individuals, suggesting these responses do not contribute to diurnal variation in orthostatic tolerance.
Lewis et al. (2011) studied this question.
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