Why the study?
Does low osmolar nonionic contrast media (Isovue-370) reduce the incidence of ventricular fibrillation compared to high osmolar ionic contrast media (Renografin-76) in patients undergoing coronary angiography?
Population
4,000 consecutive patients undergoing coronary angiography (mean age 60-63.5 years, 74-76% male)
Comparison
Isovue-370 vs Renografin-76
Design
Cohort
Follow-up
During coronary angiography
Authors
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Isovue-370 was associated with lower VF rates than Renografin-76; leaves open optimal contrast selection pending randomized trials.
Does low osmolar nonionic contrast media (Isovue-370) reduce the incidence of ventricular fibrillation compared to high osmolar ionic contrast media (Renografin-76) in patients undergoing coronary angiography?
The use of low osmolar nonionic contrast media significantly reduces the incidence of ventricular fibrillation during coronary angiography compared to high osmolar ionic contrast media.
Missri et al. (1990) studied this question.
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