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December 12, 2011Acta Anaesthesiologica Scandinavica

Lactate levels predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery

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Why the study?

Does an initial post-operative lactate level ≥4.5 mmol/l predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery?

Population

206 children undergoing congenital heart surgery from 2006 to 2007

Comparison

Initial post-operative lactate level ≥4.5 mmol/l vs Initial post-operative lactate level <4.5 mmol/l

Design

Cohort

Authors

LML. MAARSLETMMMichael MöllerRDRolf Dall

Discussion

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Member takes

Overview

May flag high-risk pediatric congenital heart surgery patients for closer monitoring; hypothesis-generating and requires prospective validation before changing practice.

Structured PICO

Does an initial post-operative lactate level ≥4.5 mmol/l predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery?

P
Population
206 children undergoing congenital heart surgery from 2006 to 2007
I
Intervention
Initial post-operative lactate level ≥4.5 mmol/l
C
Comparator
Initial post-operative lactate level <4.5 mmol/l
O
Outcome
Mortality and need for peritoneal dialysis (PD)hard clinical

Initial post-operative lactate levels ≥4.5 mmol/l strongly predict mortality and the need for peritoneal dialysis in children following congenital heart surgery.

Limitations

  • Low number of deaths limited confounder analysis

Cite This Study

MAARSLET et al. (2011) studied this question.

synapsesocial.com/papers/6a70d62de5469ee92be181cbhttps://doi.org/10.1111/j.1399-6576.2011.02588.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The RACHS-1 risk categories reflect mortality and length of stay in a Danish population of children operated for congenital heart disease☆2005 · 103 citations
  2. 2Serial blood lactate levels as a predictor of mortality in children after cardiopulmonary bypass surgery2008 · 71 citations
  3. 3The strong ion gap predicts mortality in children following cardiopulmonary bypass surgery*2005 · 81 citations
  4. 4Serum lactate as a predictor of mortality after paediatric cardiac surgery1997 · 117 citations